Description

5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride is a high-purity, functionalized quinoline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceutical intermediates and active ingredients. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Chemical Biology Probe: Used in medicinal chemistry to study enzyme inhibition, receptor binding, and other biological pathways due to its functional hydrazino group.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or functional materials with specific electronic properties.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry and medicinal chemistry.

Basic Information

Item	Details
Product Name	5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride
CAS No.	1170536-28-3
Molecular Formula	C₁₂H₁₅Cl₂N₃
Molecular Weight	272.17 g/mol
Synonyms	5-Chloro-3-ethyl-2-hydrazinyl-8-methylquinoline hydrochloride; 2-Hydrazino-5-chloro-3-ethyl-8-methylquinoline hydrochloride; 1170536-28-3; 5-Chloro-3-ethyl-8-methylquinolin-2-yl)hydrazine hydrochloride; Quinoline, 5-chloro-3-ethyl-2-hydrazino-8-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.