Description

2-Amino-6-Fluoro-3-Methylquinoline Hydrochloride is a high-purity, functionalized quinoline derivative essential for advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active compounds. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate its specific fluorine and amino-substituted quinoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, organic light-emitting diodes (OLEDs), and specialty dyes.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of focused libraries for high-throughput screening.
• Fluorinated Compound Synthesis: The fluorine atom at the 6-position makes it a valuable synthon for introducing fluorine into target molecules to modulate their metabolic stability, lipophilicity, and bioavailability.

Basic Information

Product Name	2-Amino-6-Fluoro-3-Methylquinoline Hydrochloride
CAS No.	1170267-22-7
Molecular Formula	C10H10FN2·HCl
Molecular Weight	212.66 g/mol (Free base) 249.11 g/mol (Hydrochloride salt)
Synonyms	6-Fluoro-3-methylquinolin-2-amine hydrochloride; 2-Amino-6-fluoro-3-methylquinoline HCl; 2-Amino-6-fluoro-3-methylquinoline monohydrochloride; 3-Methyl-6-fluoroquinolin-2-amine hydrochloride; 1170267-22-7; Quinoline, 2-amino-6-fluoro-3-methyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Fluoro-3-Methylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.