Description

n-(2,2,2-Trifluoroethyl)Cyclopropanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its cyclopropylamine core and trifluoroethyl substituent. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic disorders. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in CNS and metabolic disease research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the cyclopropylamine moiety.
• Ligand & Catalyst Synthesis: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Fluorinated Compound Library: An essential component for creating diverse screening libraries in drug discovery due to the presence of the trifluoroethyl group, which can improve metabolic stability and membrane permeability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	n-(2,2,2-Trifluoroethyl)Cyclopropanamine Hydrochloride
CAS No.	1169952-82-2
Molecular Formula	C5H9ClF3N
Molecular Weight	175.58 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)cyclopropanamine hydrochloride; N-(2,2,2-Trifluoroethyl)cyclopropanamine HCl; Cyclopropanamine, N-(2,2,2-trifluoroethyl)-, hydrochloride; 1-Cyclopropyl-2,2,2-trifluoroethylamine hydrochloride; (1-(2,2,2-Trifluoroethyl)cyclopropyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethyl)Cyclopropanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.