Description

2-Chloro-8-Methylquinazoline is a versatile and high-value heterocyclic building block, primarily utilized in advanced organic synthesis. Its core value lies in its reactive chloro substituent and methylated quinazoline scaffold, making it an essential intermediate for constructing complex molecules. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinazoline core's bioactivity.
• Material Science: Serves as a precursor for creating specialized organic ligands, dyes, and photoactive compounds.
• Academic & Contract Research: Essential reagent for method development and exploratory chemistry in university and CRO laboratories.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Chloro-8-Methylquinazoline
CAS No.	1169786-94-0
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	8-Methyl-2-chloroquinazoline; 2-Chloro-8-methyl-quinazoline; Quinazoline, 2-chloro-8-methyl-; 2-Chloro-8-methyl-1,3-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Methylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.