Description

4-Azabicyclo[3.1.1]heptane-5-carboxylic acid is a high-purity bicyclic organic compound featuring a carboxylic acid functional group on a constrained azabicyclic scaffold. This unique structure makes it a valuable and versatile advanced pharmaceutical intermediate and key building block for medicinal chemistry research and drug discovery. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors to synthesize novel active pharmaceutical ingredients (APIs) and explore new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used to create constrained peptidomimetics and to introduce rigid, three-dimensional geometry into lead compounds for structure-activity relationship (SAR) studies.
• Ligand and Probe Synthesis: Serves as a core structure for developing chemical probes and ligands targeting specific enzymes or receptors in biochemical assays.
• Agrochemical Research: Potential intermediate in the development of new herbicides or plant growth regulators with novel modes of action.
• Material Science: Can be used as a monomer or precursor for synthesizing specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	4-Azabicyclo[3.1.1]heptane-5-carboxylic Acid
CAS No.	1169708-23-9
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	5-Carboxy-4-azabicyclo[3.1.1]heptane; 4-Aza-bicyclo[3.1.1]heptane-5-carboxylic acid; Bicyclo[3.1.1]heptane-5-carboxylic acid, 4-aza-; 4-Azabicyclo[3.1.1]heptane-5-carboxylic acid; 5-Carboxy-4-azabicyclo[3.1.1]heptane; 4-Azabicyclo[3.1.1]heptane-5-carboxylic acid (CAS 1169708-23-9)
EINECS	Contact for details

Quality Control

Every batch of 4-Azabicyclo[3.1.1]heptane-5-carboxylic acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material produced under current Good Manufacturing Practice (cGMP) guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.