Description

(R)-1-(Pyridin-3-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis. This compound serves as a critical intermediate in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where its specific stereochemistry is vital for biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutics, particularly in areas requiring precise molecular targeting.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiopure drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands for catalytic asymmetric synthesis.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	(R)-1-(Pyridin-3-Yl)Ethanamine Hydrochloride
CAS No.	1169576-97-9
Molecular Formula	C7H11N2·HCl
Molecular Weight	158.63 g/mol (Free base: 122.18 g/mol)
Synonyms	(R)-1-(3-Pyridyl)ethylamine hydrochloride; (R)-α-Methyl-3-pyridinemethanamine hydrochloride; (R)-1-(Pyridin-3-yl)ethan-1-amine hydrochloride; (R)-3-(1-Aminoethyl)pyridine hydrochloride; (R)-(-)-1-(3-Pyridyl)ethylamine HCl; (R)-NSC 405124; (R)-Pyridin-3-ylethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(Pyridin-3-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.