Description

(R)-α-Ethyl-4-Fluorobenzylamine Hydrochloride is a high-purity chiral amine salt, specifically the hydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs). It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Development: Serves as a precursor in the synthesis of chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Ligand Synthesis: Building block for creating chiral ligands used in transition metal catalysis.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Used in university and corporate research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	(R)-α-Ethyl-4-Fluorobenzylamine Hydrochloride
CAS No.	1169576-95-7
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	(R)-1-(4-Fluorophenyl)propan-1-amine hydrochloride; (R)-α-Ethyl-4-fluorobenzylamine HCl; (R)-1-Amino-1-(4-fluorophenyl)propane hydrochloride; (R)-4-Fluoro-α-ethylbenzylamine hydrochloride; (R)-Fenfluramine impurity standard; (R)-1-(4-Fluorophenyl)propylamine hydrochloride; Benzenemethanamine, 4-fluoro-α-ethyl-, (αR)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-α-Ethyl-4-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral purity is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.