Description

(R)-1-(2-Fluorophenyl)Propan-1-Amine Hydrochloride CAS NO 1168139-44-3 is a high-purity chiral amine building block, specifically the hydrochloride salt of the (R)-enantiomer. This compound is a critical intermediate in the synthesis of advanced pharmaceutical active ingredients, particularly those targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Employed in the synthesis of candidate compounds for pharmacological evaluation and toxicology studies.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Applied in the multi-step synthesis of complex, high-value specialty chemicals beyond pharmaceuticals.

Basic Information

Product Name	(R)-1-(2-Fluorophenyl)Propan-1-Amine Hydrochloride
CAS No.	1168139-44-3
Molecular Formula	C9H12FN•HCl
Molecular Weight	189.66 g/mol
Synonyms	(R)-1-(2-Fluorophenyl)-1-propanamine hydrochloride; (R)-1-Amino-1-(2-fluorophenyl)propane hydrochloride; (R)-2-Fluoroamphetamine hydrochloride; (R)-FPA HCl; (R)-1-(2-Fluorophenyl)propylamine hydrochloride; (R)-1-(o-Fluorophenyl)propan-1-amine hydrochloride; (R)-Norephedrine, 2-fluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Fluorophenyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.