Description

(R)-1-(2-Chlorophenyl)Ethanamine-Hcl is a high-purity chiral amine building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and insecticides where the (R)-enantiomer provides specific biological efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce stereoselectivity.
• Fine Chemical Building Block: Employed in academic and industrial R&D for constructing complex organic molecules with defined stereocenters for material science and specialty chemicals.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC and SFC.

Basic Information

Product Name	(R)-1-(2-Chlorophenyl)Ethanamine-Hcl
CAS No.	1167414-92-7
Molecular Formula	C8H11Cl2N
Molecular Weight	192.09 g/mol
Synonyms	(R)-1-(2-Chlorophenyl)ethanamine hydrochloride; (R)-1-(2-Chlorophenyl)ethylamine hydrochloride; (R)-α-Methyl-2-chlorobenzylamine hydrochloride; (R)-2-Chloro-α-methylbenzylamine hydrochloride; (R)-1-(o-Chlorophenyl)ethylamine HCl; (R)-(-)-1-(2-Chlorophenyl)ethylamine hydrochloride; (R)-1-(2-Chloro-phenyl)-ethylamine hydrochloride; (R)-o-Chloro-α-methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Chlorophenyl)Ethanamine-Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.