Description

(R)-(+)-1-(4-Chlorophenyl)Ethylamine-Hcl CAS NO 1167414-87-0 is a high-purity chiral amine building block, specifically the hydrochloride salt of the (R)-enantiomer. This compound is a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its defined stereochemistry is essential for biological activity. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific enantiomer can provide enhanced efficacy and reduced environmental impact.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in stereoselective synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & Industrial Research: A valuable standard and building block in medicinal chemistry and process development research.

Basic Information

Product Name	(R)-(+)-1-(4-Chlorophenyl)Ethylamine Hydrochloride
CAS No.	1167414-87-0
Molecular Formula	C8H11Cl2N
Molecular Weight	192.09 g/mol
Synonyms	(R)-(+)-1-(4-Chlorophenyl)ethylamine hydrochloride; (R)-1-(4-Chlorophenyl)ethanamine hydrochloride; (R)-α-Methyl-4-chlorobenzylamine hydrochloride; (R)-4-Chloro-α-methylbenzylamine hydrochloride; (R)-p-Chloro-α-methylbenzylamine hydrochloride; (R)-1-(p-Chlorophenyl)ethylamine HCl; (R)-CPEA HCl
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(4-Chlorophenyl)Ethylamine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.