Description

3-Bromo-5-Chloro-6-Azaindole is a high-purity halogenated azaindole derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its unique heterocyclic scaffold, which serves as a privileged structure for medicinal chemistry research and drug discovery. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles for further functionalization.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides and fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science Research: Potential monomer or precursor for creating specialized organic electronic materials or ligands for catalysis.

Basic Information

Product Name	3-Bromo-5-Chloro-6-Azaindole
CAS No.	1167056-96-3
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	3-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-bromo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-5-chloro-; 3-Bromo-5-chloro-7-azaindole; 5-Chloro-3-bromo-7-azaindole; 3-Bromo-5-chloro-1H-7-azaindole; 3-Br-5-Cl-6-Azaindole; 6-Azaindole, 3-bromo-5-chloro-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-6-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.