Description

6-Fluoro-3-Hydroxy-Quinoline-4-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. Its unique fluorinated quinoline scaffold makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated quinolone antibiotics and other bioactive molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced activity and stability.
• Material Science: Serves as a building block for creating functionalized organic ligands and metal-organic frameworks (MOFs) with specific electronic or photophysical properties.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a versatile scaffold for library synthesis in drug discovery programs.
• Fluorescent Probe Development: The quinoline core can be utilized to develop novel fluorescent dyes and sensors for biochemical and diagnostic applications.

Basic Information

Product Name	6-Fluoro-3-Hydroxy-Quinoline-4-Carboxylic Acid
CAS No.	1167056-89-4
Molecular Formula	C₁₀H₆FNO₃
Molecular Weight	207.16 g/mol
Synonyms	6-Fluoro-3-hydroxy-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-3-hydroxy-; 6-Fluoro-3-hydroxyquinoline-4-carboxylic acid; 6-Fluoro-3-hydroxy-1H-quinoline-4-carboxylic acid; 6-Fluoro-3-oxo-3,4-dihydroquinoline-4-carboxylic acid; 6-Fluoro-3-hydroxy-4-carboxyquinoline; 3-Hydroxy-6-fluoroquinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Hydroxy-Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.