Description

4-Fluoro-7-Nitro-2,3-Dihydro-1H-Indole is a high-purity, synthetically valuable heterocyclic building block, identified by CAS NO 1167056-12-3. This compound is essential for advanced organic synthesis, serving as a key precursor in the development of novel pharmaceuticals and agrochemicals. It is primarily required by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its unique fluorinated nitro-indole structure.
• Material Science: Serves as a precursor for specialty dyes, pigments, and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or linker in the design of molecular tools and biochemical assays.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory synthesis projects.

Basic Information

Product Name	4-Fluoro-7-Nitro-2,3-Dihydro-1H-Indole
CAS No.	1167056-12-3
Molecular Formula	C8H7FN2O2
Molecular Weight	182.15 g/mol
Synonyms	4-Fluoro-7-nitroindoline; 7-Nitro-4-fluoro-2,3-dihydro-1H-indole; 1H-Indole, 4-fluoro-7-nitro-2,3-dihydro-; 4-Fluoro-7-nitroindoline; 2,3-Dihydro-4-fluoro-7-nitro-1H-indole; 1167056-12-3; 4-F-7-NO2-indoline
EINECS	Contact for details

Quality Control

Our 4-Fluoro-7-Nitro-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.