Description

Phenol, 3-Amino-5-Fluoro- is a fluorinated aminophenol derivative, a versatile and high-value aromatic building block. This compound is critical for synthesizing complex molecules where the introduction of both amino and fluorine functionalities is required. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective research programs.
• Agrochemical Synthesis: Used to construct advanced intermediates for novel herbicides, fungicides, and insecticides, leveraging the metabolic stability imparted by the fluorine atom.
• Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers, dyes, and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and as a directing group in metal-catalyzed transformations.
• Bioconjugation & Probe Development: Useful for labeling and modifying biomolecules in diagnostic and biochemical research due to its reactive amino and phenolic groups.

Basic Information

Product Name	Phenol, 3-Amino-5-Fluoro-
CAS No.	1167055-92-6
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	3-Amino-5-fluorophenol; 5-Fluoro-3-aminophenol; 3-Amino-5-fluorophenol; 1-Amino-3-fluoro-5-hydroxybenzene; 5-Fluoro-m-aminophenol; 3-Fluoro-5-hydroxyaniline; m-Amino-p-fluorophenol; 3-Fluoro-5-aminophenol
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-fluorophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthetic route. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.