Description

2,4,7-Trichloro-6-Bromoquinazoline is a halogenated quinazoline derivative, a versatile and highly functionalized heterocyclic building block. Its unique substitution pattern makes it a critical intermediate for synthesizing complex molecules with targeted biological activity. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazoline core.
• Material Science: Acts as a building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive halogen sites.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and the exploration of new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2,4,7-Trichloro-6-Bromoquinazoline
CAS No.	1166378-32-0
Molecular Formula	C8H2BrCl3N2
Molecular Weight	326.37 g/mol
Synonyms	6-Bromo-2,4,7-trichloroquinazoline; 2,4,7-Trichloro-6-bromoquinazoline; Quinazoline, 6-bromo-2,4,7-trichloro-; 6-Bromo-2,4,7-trichloro-quinazoline; Bromo-trichloro quinazoline derivative
EINECS	Contact for details

Quality Control

Every batch of 2,4,7-Trichloro-6-Bromoquinazoline is produced and analyzed under strict quality management protocols. We ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.