Description

6-Bromo-7-Chloroquinazoline-2,4-Diol is a high-purity, heterocyclic organic compound serving as a critical advanced pharmaceutical intermediate. Its value lies in its functionalized quinazoline core, which is a privileged scaffold in medicinal chemistry for designing targeted therapeutic agents. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on kinase inhibitor programs and novel anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule kinase inhibitors for oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse quinazoline-based compound libraries.
• Biochemical Tool Compound: Potential use in developing assay probes to study specific enzyme pathways and biological mechanisms.
• Academic & Contract Research: Employed in university and CRO settings for exploratory research in drug discovery and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-7-Chloroquinazoline-2,4-Diol
CAS No.	1166378-30-8
Molecular Formula	C8H4BrClN2O2
Molecular Weight	275.49 g/mol
Synonyms	6-Bromo-7-chloro-2,4-dihydroxyquinazoline; 2,4-Dihydroxy-6-bromo-7-chloroquinazoline; 7-Chloro-6-bromoquinazoline-2,4(1H,3H)-dione; 6-Bromo-7-chloroquinazoline-2,4(1H,3H)-dione; Quinazoline-2,4-diol, 6-bromo-7-chloro-; 1166378-30-8
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Chloroquinazoline-2,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.