Description

(Z)-2-(3-Chlorophenyl)-3-[2-(Methylsulfanyl)-3-Quinolinyl]-2-Propenenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline-based molecular architecture. This compound matters for its critical role in the synthesis of complex bioactive molecules, offering a precise chemical handle for medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized quinoline core.
• Agrochemical Development: Acts as a precursor in the research and development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and target identification.
• Organic Synthesis: Employed in advanced organic reactions, such as cross-coupling and cyclization, to construct complex heterocyclic systems.

Basic Information

Product Name	(Z)-2-(3-Chlorophenyl)-3-[2-(Methylsulfanyl)-3-Quinolinyl]-2-Propenenitrile
CAS No.	1164558-83-1
Molecular Formula	C20H13ClN2S
Molecular Weight	348.85 g/mol
Synonyms	(Z)-2-(3-Chlorophenyl)-3-(2-(methylthio)quinolin-3-yl)acrylonitrile; 2-(3-Chlorophenyl)-3-[2-(methylsulfanyl)-3-quinolinyl]-2-propenenitrile; 3-Quinolineacrylonitrile, 2-(3-chlorophenyl)-3-[2-(methylthio)-]; (Z)-2-(3-Chlorophenyl)-3-(2-(methylmercapto)-3-quinolyl)acrylonitrile; (Z)-2-(3-Chlorophenyl)-3-(2-(methylsulfanyl)-3-quinolyl)-2-propenenitrile; (Z)-2-(3-Chlorophenyl)-3-(2-(methylthio)-3-quinolyl)acrylonitrile
EINECS	Contact for details

Quality Control

Our (Z)-2-(3-Chlorophenyl)-3-[2-(Methylsulfanyl)-3-Quinolinyl]-2-Propenenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.