Description

1-(Phenoxycarbonyl)Pyrrolidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for constructing specific molecular architectures, particularly in the development of novel therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those containing pyrrolidine scaffolds.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors for therapeutic applications.
• Peptidomimetic Synthesis: Serves as a crucial component for creating peptidomimetics, which are molecules that mimic peptides.
• Chemical Biology Probes: Employed in the design and synthesis of probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	1-(Phenoxycarbonyl)Pyrrolidine-2-Carboxylic Acid
CAS No.	1161602-22-7
Molecular Formula	C12H13NO4
Molecular Weight	235.24 g/mol
Synonyms	1-(Phenoxycarbonyl)-L-proline; 1-[(Phenyloxy)carbonyl]-2-pyrrolidinecarboxylic Acid; 1-Phenoxycarbonylproline; Pyrrolidine-2-carboxylic acid, 1-(phenoxycarbonyl)-; L-Proline, 1-(phenoxycarbonyl)-; 1-Carbobenzyloxy-L-proline (Cbz-L-Pro-OH); N-Carbobenzyloxy-L-proline; N-Cbz-L-proline
EINECS	Contact for details

Quality Control

Our 1-(Phenoxycarbonyl)Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.