Description

2-Amino-4-Methylpentanoic Acid Isopropylamide is a specialized amino acid derivative with a unique amide functionalization. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, bioactive peptides, and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptidomimetics & Bioactive Peptide Synthesis: Used to incorporate modified leucine analogs into peptide chains, enhancing stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Material Science: Potential monomer or precursor for designing functional polymers and dendrimers with tailored properties.
• Chemical Biology Probes: Useful for labeling, cross-linking, or modifying biomolecules to study protein interactions and cellular pathways.

Basic Information

Item	Detail
Product Name	2-Amino-4-Methylpentanoic Acid Isopropylamide
CAS No.	1161070-80-9
Molecular Formula	C9H20N2O
Molecular Weight	172.27 g/mol
Synonyms	L-Leucine Isopropylamide; Isopropyl 2-Amino-4-methylpentanoamide; 2-Amino-4-methylpentanamide, N-(1-methylethyl)-; (S)-2-Amino-4-methylpentanoic acid isopropylamide; Leucine Isopropyl Amide; N-Isopropylleucinamide; (2S)-2-Amino-4-methyl-N-(propan-2-yl)pentanamide
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Methylpentanoic Acid Isopropylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.