Description

5-Bromo-3-Hydroxypicolinic Acid is a versatile and high-purity heterocyclic building block used in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a bromine substituent with a hydroxypicolinic acid core, enabling precise chemical modifications. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Chemical Synthesis: Serves as a versatile precursor for coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for introducing the hydroxypicolinate moiety into larger molecules.
• Ligand and Chelator Development: The carboxylic acid and hydroxyl groups make it a candidate for designing metal-chelating ligands in catalysis or diagnostic agents.
• Material Science: Potential use in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	5-Bromo-3-Hydroxypicolinic Acid
CAS No.	1160994-90-0
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	3-Hydroxy-5-bromopyridine-2-carboxylic acid; 5-Bromo-3-hydroxypyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-bromo-3-hydroxy-; 5-Bromo-3-hydroxy-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Hydroxypicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.