Description

4-Carbamoylbicyclo[2.2.2]octane-1-carboxylic acid is a high-purity, synthetically derived bicyclic organic compound featuring both carboxylic acid and carboxamide functional groups. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring rigid, three-dimensional bicyclic scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for creating focused libraries for high-throughput screening.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: The carboxylic acid and amide groups provide handles for creating chelating ligands or organocatalysts.
• Material Science Precursor: Potential use in synthesizing monomers for specialty polymers with unique thermal or mechanical properties.
• Academic & Institutional Research: Employed in organic synthesis methodology development and as a model compound in teaching and research.

Basic Information

Item	Details
Product Name	4-Carbamoylbicyclo[2.2.2]octane-1-carboxylic Acid
CAS No.	1160591-75-2
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	1-Carboxybicyclo[2.2.2]octane-4-carboxamide; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-carbamoyl-; 4-Carbamoylbicyclo[2.2.2]octane-1-carboxylate; 4-Aminocarbonylbicyclo[2.2.2]octane-1-carboxylic Acid; 1,4-Bicyclo[2.2.2]octanedicarboxylic acid monoamide; BCOCA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 4-Carbamoylbicyclo[2.2.2]octane-1-carboxylic acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against comprehensive specifications using advanced analytical techniques including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.