Description

2-Chloro-5-Isopropylbenzoic Acid is a high-purity benzoic acid derivative characterized by its chloro and isopropyl substituents, which impart unique steric and electronic properties. This compound is a critical pharmaceutical intermediate and versatile organic building block for advanced synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where its specific substitution pattern modifies material properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects in medicinal chemistry and process optimization.

Basic Information

Product Name	2-Chloro-5-Isopropylbenzoic Acid
CAS No.	1160575-02-9
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	5-Isopropyl-2-chlorobenzoic Acid; 2-Chloro-5-(1-methylethyl)benzoic Acid; Benzoic acid, 2-chloro-5-(1-methylethyl)-; 2-Chloro-5-propan-2-ylbenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Isopropylbenzoic Acid is manufactured under a cGMP-compliant quality management system, ensuring batch-to-batch consistency for critical applications. Each lot is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.