Description

5-Bromo-4-Chloro-2-Iodoanisole is a high-purity halogenated anisole derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it an essential intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing complex halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific halogen pattern influences biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the presence of iodine and bromine.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for catalysis and molecular recognition studies.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Iodoanisole
CAS No.	1160574-88-8
Molecular Formula	C7H5BrClIO
Molecular Weight	346.38 g/mol
Synonyms	1-Bromo-2-chloro-5-iodo-4-methoxybenzene; 2-Iodo-5-bromo-4-chloroanisole; 4-Chloro-5-bromo-2-iodoanisole; Anisole, 5-bromo-4-chloro-2-iodo-; Benzene, 1-bromo-2-chloro-5-iodo-4-methoxy-; 5-Bromo-4-chloro-2-iodo-1-methoxybenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Iodoanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.