Description

5-Bromo-2-Iodo-4-Nitrotoluene is a high-purity halogenated aromatic compound, specifically a multi-substituted toluene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and nitro functional groups on the same aromatic ring, makes it an exceptionally versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical research, and the creation of specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores for bioactivity or as synthetic handles for further functionalization.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the halogen and nitro groups can contribute to binding affinity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine and bromine atoms offer orthogonal reactivity for sequential functionalization.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex, color-fast dyes and organic pigments due to its electron-withdrawing nitro group and halogen substituents.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university laboratories and contract research organizations (CROs).

Basic Information

Product Name	5-Bromo-2-Iodo-4-Nitrotoluene
CAS No.	1160573-63-6
Molecular Formula	C7H5BrINO2
Molecular Weight	341.93 g/mol
Synonyms	1-Bromo-4-methyl-2-iodo-5-nitrobenzene; 2-Iodo-5-bromo-4-nitrotoluene; Toluene, 5-bromo-2-iodo-4-nitro-; 4-Nitro-5-bromo-2-iodotoluene; 5-Bromo-2-iodo-4-methylnitrobenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-4-Nitrotoluene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.