Description

8-Chloro-2-(3-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride and halogenated quinoline core. This compound matters for its critical role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides due to its bioactive quinoline scaffold.
• Material Science Research: Serves as a precursor for creating functionalized organic ligands and complex molecules for advanced material applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	8-Chloro-2-(3-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-83-1
Molecular Formula	C19H15Cl2NO2
Molecular Weight	360.23 g/mol
Synonyms	8-Chloro-2-(3-isopropoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Isopropoxyphenyl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-(3-propan-2-yloxyphenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 8-chloro-2-[3-(1-methylethoxy)phenyl]-; 1160263-83-1; 8-Cl-2-(3-iso-PrO-Ph)-Quinoline-4-COCl
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(3-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.