Description

7-Chloro-8-Methyl-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of significant value for its role as a key building block in the synthesis of complex organic molecules, particularly active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, particularly in oncology and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and pesticides with enhanced efficacy.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic frameworks via amidation or esterification reactions.
• Material Science: Potential intermediate for the development of specialty polymers, ligands, or functional materials with specific optical or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences sector.

Basic Information

Product Name	7-Chloro-8-Methyl-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-80-8
Molecular Formula	C21H19Cl2NO2
Molecular Weight	388.29 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 7-chloro-8-methyl-2-[3-(propoxy)phenyl]-; 2-(3-Propoxyphenyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; 7-Chloro-8-methyl-2-(3-propoxy-phenyl)-quinoline-4-carbonyl chloride; 1160263-80-8; AKOS025247065; 4-Carboxy-7-chloro-8-methyl-2-(3-propoxyphenyl)quinoline chloride
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Methyl-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.