Description

8-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate designed for advanced synthesis. Its core value lies in its reactive carbonyl chloride and halogenated quinoline structure, enabling precise derivatization for complex molecule construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, particularly those focused on creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors, antimicrobial agents, and other bioactive quinoline derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline scaffold contributes to biological activity.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other advanced materials.
• Chemical Biology Probes: Employed in the development of fluorescent tags or molecular probes for studying biological processes due to the modifiable quinoline core.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	8-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-79-5
Molecular Formula	C19H15Cl2NO2
Molecular Weight	360.24 g/mol
Synonyms	8-Chloro-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Propoxyphenyl)-8-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-[3-(propoxy)phenyl]-; 1160263-79-5; 8-Chloro-2-(3-propoxy-phenyl)-quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to GMP-grade standards in handling and documentation ensures the material is suitable for demanding research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.