Description

7-Chloro-2-(3-Methoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive acid chloride functional group. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers specializing in the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, particularly in oncology and anti-infective research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in pharmaceutical labs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring the quinoline core structure.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional laboratories for chemical methodology development and bioorganic studies.

Basic Information

Product Name	7-Chloro-2-(3-Methoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160263-68-2
Molecular Formula	C19H13Cl2NO2
Molecular Weight	366.22 g/mol
Synonyms	4-Chlorocarbonyl-7-chloro-2-(3-methoxyphenyl)-8-methylquinoline; 7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid chloride; 8-Methyl-7-chloro-2-(3-methoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Methoxyphenyl)-7-chloro-8-methyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 7-chloro-2-(3-methoxyphenyl)-8-methyl-
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(3-Methoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.