Description

2-(3-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-purity, multi-functional organic intermediate designed for advanced chemical synthesis. This compound is critical for research and development in pharmaceutical and agrochemical sectors, where precise molecular architecture is required. It serves as a key building block for medicinal chemists and process development scientists seeking to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the quinoline core for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, bioconjugation, or as a core scaffold in the design of chemical probes and enzyme inhibitors.
• Academic & Industrial R&D: A valuable reagent for method development, library synthesis, and exploring new chemical spaces in contract research organizations (CROs) and university laboratories.

Basic Information

Product Name	2-(3-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160263-63-7
Molecular Formula	C₁₇H₁₀BrCl₂NO
Molecular Weight	395.08 g/mol
Synonyms	8-Chloro-2-(3-bromophenyl)quinoline-4-carbonyl chloride; 2-(3-Bromophenyl)-8-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(3-bromophenyl)-; 1160263-63-7; 8-Chloro-2-(3-bromophenyl)-4-quinolinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.