Description

2-(4-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-purity, multi-functional chemical building block designed for advanced synthetic chemistry. This compound is valued for its reactive carbonyl chloride group and halogenated aromatic-quinoline core, enabling precise molecular construction. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: An essential building block for constructing complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale production.
• Ligand & Catalyst Development: The quinoline moiety makes it suitable for developing novel metal-organic frameworks (MOFs) and catalytic ligands.

Basic Information

Product Name	2-(4-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160263-61-5
Molecular Formula	C₁₇H₈BrCl₂NO
Molecular Weight	409.06 g/mol
Synonyms	8-Chloro-2-(4-bromophenyl)quinoline-4-carbonyl chloride; 2-(4-Bromophenyl)-8-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(4-bromophenyl)-; 1160263-61-5; 2-(p-Bromophenyl)-8-chloroquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)-8-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.