Description

8-Chloro-2-(2-Chlorophenyl)Quinoline-4-Carbonyl Chloride is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its reactive acid chloride group and halogenated quinoline core, which serve as key building blocks for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated quinoline structure.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: The quinoline nitrogen and chlorophenyl group make it a useful scaffold for creating novel ligands in coordination chemistry and catalysis.
• Fluorescent Probe Synthesis: Acts as a starting material for synthesizing quinoline-based dyes and probes used in biochemical sensing and imaging.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific halogenated motif.

Basic Information

Product Name	8-Chloro-2-(2-Chlorophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-59-1
Molecular Formula	C17H8Cl3NO
Molecular Weight	348.61 g/mol
Synonyms	2-(2-Chlorophenyl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-(2-chlorophenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(2-chlorophenyl)-; 2-(2-Chlorophenyl)-8-chloro-4-quinolinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(2-Chlorophenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.