Description

8-Chloro-2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and halogenated quinoline core. This compound matters for its critical role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides due to its bioactive quinoline scaffold.
• Material Science Research: Serves as a precursor for creating organic ligands, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Details
Product Name	8-Chloro-2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-57-9
Molecular Formula	C17H8Cl3NO
Molecular Weight	356.61 g/mol
Synonyms	8-Chloro-2-(3-chlorophenyl)-4-quinolinecarbonyl chloride; 2-(3-Chlorophenyl)-8-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(3-chlorophenyl)-; 1160263-57-9; 8-Chloro-2-(3-chloro-phenyl)-quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and reliable supply chain integrity makes us a trusted partner for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.