Description

6-Chloro-2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate characterized by its quinoline core and dual chloride functionalities. This compound matters for its critical role as a versatile building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other quinoline-based therapeutic pathways.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents, including herbicides and fungicides with quinoline scaffolds.
• Material Science Research: Used in the creation of organic ligands, coordination complexes, and functionalized polymers for electronic or photonic applications.
• Chemical Biology Probes: Serves as a starting material for synthesizing fluorescent tags or activity-based probes for biological target identification.
• Academic & Contract Research: Essential reagent for methodology development and exploratory organic synthesis in university and CRO laboratories.

Basic Information

Product Name	6-Chloro-2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-49-9
Molecular Formula	C19H15Cl2NO2
Molecular Weight	360.23 g/mol
Synonyms	6-Chloro-2-(2-isopropoxyphenyl)quinoline-4-carbonyl chloride; 2-(2-Isopropoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-[2-(1-methylethoxy)phenyl]-; 6-Chloro-2-(2-propan-2-yloxyphenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.