Description

6-Chloro-2-(2-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex quinoline-based molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing process of complex APIs, particularly those containing the quinoline scaffold.
• Fine Chemical Production: Employed in the production of specialty chemicals, dyes, and advanced materials requiring specific quinoline derivatives.
• Agrochemical Research: Potential intermediate in the development of new agrochemicals and pesticides.

Basic Information

Product Name	6-Chloro-2-(2-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-47-7
Molecular Formula	C19H15Cl2NO2
Molecular Weight	360.24 g/mol
Synonyms	6-Chloro-2-(2-propoxyphenyl)quinoline-4-carbonyl chloride; 2-(2-Propoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 6-chloro-2-(2-propoxyphenyl)-; 1160263-47-7
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(2-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.