Description

6-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional organic intermediate with significant synthetic utility. Its core value lies in its dual reactive sites—the acid chloride and the chloro-quinoline moiety—which enable its use as a key building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel quinoline-based drug candidates, particularly for anti-malarial, anti-cancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline scaffold contributes to biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the creation of fluorescent tags or affinity probes for studying biological processes due to the modifiable quinoline structure.
• Catalyst Ligand Preparation: Utilized for synthesizing novel nitrogen-containing ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-41-1
Molecular Formula	C21H17Cl2NO2
Molecular Weight	386.27 g/mol
Synonyms	6-Chloro-2-(4-isobutoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Isobutoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Chlorocarbonyl-6-chloro-2-(4-isobutoxyphenyl)quinoline; Quinoline-4-carbonyl chloride, 6-chloro-2-(4-isobutoxyphenyl)-; 1160263-41-1
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.