Description

6-Chloro-2-(4-Methoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its core value lies in its dual reactive sites, the acid chloride and the chloro-quinoline moiety, which enable its use as a key precursor for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or possessing anti-malarial properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides due to the bioactive quinoline scaffold.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport layers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Fluorescent Probe Synthesis: The quinoline core is utilized to develop fluorescent dyes and sensors for biological imaging and chemical detection.
• Custom Synthesis and R&D: Provides a versatile starting point for contract research organizations (CROs) and academic institutions engaged in novel chemical entity discovery.

Basic Information

Product Name	6-Chloro-2-(4-Methoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-31-9
Molecular Formula	C18H11Cl2NO2
Molecular Weight	344.19 g/mol
Synonyms	6-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Methoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Chlorocarbonyl-6-chloro-2-(4-methoxyphenyl)quinoline; Quinoline-4-carbonyl chloride, 6-chloro-2-(4-methoxyphenyl)-; 1160263-31-9
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(4-Methoxyphenyl)Quinoline-4-Carbonyl Chloride is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of advanced R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.