Description

2-(3-Bromophenyl)-6-Chloroquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex quinoline-based molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Synthesis: Serves as a crucial building block in multi-step synthetic routes for active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate for developing new crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(3-Bromophenyl)-6-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160263-26-2
Molecular Formula	C₁₇H₁₀BrCl₂NO
Molecular Weight	395.08 g/mol
Synonyms	6-Chloro-2-(3-bromophenyl)quinoline-4-carbonyl chloride; 2-(3-Bromophenyl)-6-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3-bromophenyl)-6-chloro-; 1160263-26-2; 2-(3-Bromophenyl)-6-chloroquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)-6-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened to prevent decomposition. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.