Description

2-(4-sec-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound matters because it serves as a critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require the synthesis of quinoline-based active ingredients, such as pharmaceutical R&D and fine chemical manufacturing, are the primary users of this specialized reagent.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the quinoline scaffold is active.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated quinoline structure.
• Material Science Research: Employed in the creation of organic ligands for metal-organic frameworks (MOFs) or functional materials due to its aromatic and carbonyl chloride functionalities.
• Fine Chemical Production: Serves as a versatile building block for custom synthesis and the manufacture of specialty chemicals for various industrial applications.
• Academic & Industrial R&D: A valuable reagent for chemists exploring new synthetic routes and developing compounds with potential biological activity.

Basic Information

Product Name	2-(4-sec-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160263-23-9
Molecular Formula	C20H17Cl2NO
Molecular Weight	358.26 g/mol
Synonyms	6-Chloro-2-[4-(1-methylpropyl)phenyl]quinoline-4-carbonyl chloride; 2-(4-sec-Butylphenyl)-6-chloroquinoline-4-carboxylic acid chloride; 6-Chloro-2-(4-sec-butylphenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 6-chloro-2-[4-(1-methylpropyl)phenyl]-; CAS 1160263-23-9
EINECS	Contact for details

Quality Control

Our production of 2-(4-sec-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.