Description

2-(4-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules with tailored properties. This compound is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical companies for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of quinoline-based drug candidates, including potential anti-malarial, anti-inflammatory, and anticancer agents.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Used in the creation of organic semiconductors, liquid crystals, and fluorescent dyes due to its conjugated quinoline core.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO settings.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for the discovery of new bioactive compounds.

Basic Information

Product Name	2-(4-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160263-19-3
Molecular Formula	C21H17Cl2NO
Molecular Weight	370.27 g/mol
Synonyms	6-Chloro-2-(4-butylphenyl)quinoline-4-carbonyl chloride; 2-(4-Butylphenyl)-6-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-[4-(1,1-dimethylethyl)phenyl]-; 1160263-19-3; 6-Chloro-2-(p-butylphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Butylphenyl)-6-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.