Description

6-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and complex quinoline-based aromatic structure. This compound matters for its role as a critical building block in the synthesis of advanced organic molecules, where it enables the formation of amide or ester linkages. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline dyes and high-performance pigments.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the synthesis of activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the bespoke production of complex molecules for client R&D projects.

Basic Information

Product Name	6-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-14-8
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	6-Chloro-2-(3,4-dimethylphenyl)quinoline-4-carbonyl chloride; 2-(3,4-Dimethylphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-(3,4-dimethylphenyl)-; 1160263-14-8; 6-Chloro-2-(3,4-dimethylphenyl)-4-quinolinecarbonyl chloride; 6-Chloro-2-(3,4-xylyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.