Description

6-Chloro-2-(3-Methylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a versatile building block in the development of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Material Science: Serves as a building block for creating specialized ligands, dyes, and photoactive compounds.
• Academic & Industrial R&D: Essential for method development and exploring new chemical reactions in heterocyclic and medicinal chemistry.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.

Basic Information

Product Name	6-Chloro-2-(3-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-12-6
Molecular Formula	C18H11Cl2NO
Molecular Weight	328.19 g/mol
Synonyms	6-Chloro-2-(m-tolyl)quinoline-4-carbonyl chloride; 2-(3-Methylphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-(3-methylphenyl)-; 1160263-12-6; 6-Chloro-2-(3-methylphenyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(3-Methylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.