Description

6-Chloro-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block, specifically an acid chloride derivative of a quinoline-thiophene hybrid scaffold. Its core value lies in its exceptional reactivity, serving as a crucial precursor for synthesizing complex heterocyclic compounds and advanced pharmaceutical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor research and other therapeutic areas targeting quinoline-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the quinoline-thiophene core structure.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands for metal catalysis and coordination chemistry applications.
• Fluorescent Probe Synthesis: Acts as a starting material for synthesizing fluorescent dyes and molecular probes used in bioimaging and diagnostic assays.
• Custom Synthesis & Contract Research: A vital reagent for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific molecular targets.

Basic Information

Product Name	6-Chloro-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-06-8
Molecular Formula	C14H7Cl2NOS
Molecular Weight	308.18 g/mol
Synonyms	6-Chloro-2-(thiophen-2-yl)quinoline-4-carbonyl chloride; 2-(2-Thienyl)-6-chloroquinoline-4-carbonyl chloride; 6-Chloro-2-thiophen-2-ylquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 6-chloro-2-(2-thienyl)-; 1160263-06-8
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.