Description

2-(3-Bromophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and materials science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting kinase inhibition or other quinoline-based therapeutic pathways.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides where the quinoline moiety imparts specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs or conductive polymers.
• Ligand Synthesis: Utilized in organometallic chemistry for the preparation of complex ligands used in catalysis.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent probes or photoaffinity labels for biological target identification.
• Academic & Contract Research: Essential reagent for synthetic organic chemistry research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	2-(3-Bromophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160262-79-2
Molecular Formula	C18H13BrClNO
Molecular Weight	374.66 g/mol
Synonyms	6,8-Dimethyl-2-(3-bromophenyl)quinoline-4-carbonyl chloride; 2-(3-Bromophenyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3-bromophenyl)-6,8-dimethyl-; (2-(3-Bromophenyl)-6,8-dimethylquinolin-4-yl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.