Description

2-(4-Isopropylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate primarily used in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic compounds, particularly in the development of specialized fine chemicals and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific quinoline-based molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific biological pathways where the quinoline scaffold is active.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides that require complex, functionalized heterocyclic cores.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs or conductive polymers.
• Ligand and Catalyst Development: Employed for constructing sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and colorants for high-performance applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific molecules.

Basic Information

Product Name	2-(4-Isopropylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160262-70-3
Molecular Formula	C21H20ClNO
Molecular Weight	337.84 g/mol
Synonyms	6,8-Dimethyl-2-(4-propan-2-ylphenyl)quinoline-4-carbonyl chloride; 2-(p-Isopropylphenyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[4-(1-methylethyl)phenyl]-6,8-dimethyl-; 2-(4-Isopropylphenyl)-6,8-dimethylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Isopropylphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring material that meets stringent internal standards or compendial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.