Description

2-(2-Chlorophenyl)-8-Ethylquinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials. It is specifically sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex quinoline-based molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides with quinoline scaffolds.
• Material Science Research: Serves as a precursor for creating functional organic materials, including ligands for catalysis, organic semiconductors, and fluorescent dyes.
• Chemical Biology Probes: Employed in the development of molecular probes and diagnostic agents due to its modifiable reactive sites.
• Academic & Industrial R&D: Essential for synthetic chemistry research in universities and corporate laboratories exploring new heterocyclic compounds.
• Scale-up Process Development: Used in pilot plants and kilo-labs for process optimization and route scouting for target molecules.

Basic Information

Product Name	2-(2-Chlorophenyl)-8-Ethylquinoline-4-Carbonyl Chloride
CAS No.	1160261-20-0
Molecular Formula	C19H15Cl2NO
Molecular Weight	344.24 g/mol
Synonyms	8-Ethyl-2-(2-chlorophenyl)-4-quinolinecarbonyl chloride; 2-(2-Chlorophenyl)-8-ethyl-4-quinolinecarbonyl chloride; 8-Ethyl-2-(o-chlorophenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(2-chlorophenyl)-8-ethyl-; 1160261-20-0; 2-(2-Chlorophenyl)-8-ethylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(2-Chlorophenyl)-8-Ethylquinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.