Description

2-(4-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), specialty dyes, and advanced materials who require a reliable and high-quality source of this specific quinoline derivative.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline core provides specific biological activity.
• Material Science Research: Serves as a building block for creating organic semiconductors, light-emitting materials (OLEDs), and specialty polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance quinoline dyes and pigments.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating bespoke molecular libraries.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	2-(4-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160255-86-6
Molecular Formula	C21H19Cl2NO2
Molecular Weight	388.29 g/mol
Synonyms	8-Chloro-2-[4-(butoxy)phenyl]-4-quinolinecarbonyl chloride; 2-(4-Butoxyphenyl)-8-chloro-4-quinolinecarbonyl chloride; 8-Chloro-2-(4-butoxyphenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 8-chloro-2-[4-(butoxy)phenyl]-; 1160255-86-6
EINECS	Contact for details

Quality Control

Our production of 2-(4-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.