Description

2-(4-Butoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a specialized quinoline derivative and a key acyl chloride intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the development of complex molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in the development of compounds with quinoline-based pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the quinoline structure imparts specific biological activity.
• Material Science Research: Acts as a precursor for the creation of functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Chemical Biology Probes: Employed in the development of fluorescent probes and molecular tags due to the inherent photophysical properties of the quinoline core.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs) specializing in heterocyclic chemistry.

Basic Information

Product Name	2-(4-Butoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-59-0
Molecular Formula	C22H22ClNO2
Molecular Weight	367.87 g/mol
Synonyms	8-Methyl-2-[4-(butoxy)phenyl]-4-quinolinecarbonyl chloride; 2-(4-Butoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[4-(butoxy)phenyl]-8-methyl-; 1160254-59-0; 2-(4-n-Butoxyphenyl)-8-methylquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Butoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.