Description

2-(2,5-Dimethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound matters for its critical role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those with quinoline-based scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex aromatic structure.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules via amide bond formation or further functionalization of the quinoline core.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	2-(2,5-Dimethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-47-6
Molecular Formula	C20H18ClNO3
Molecular Weight	355.82 g/mol
Synonyms	8-Methyl-2-(2,5-dimethoxyphenyl)quinoline-4-carbonyl chloride; 2-(2,5-Dimethoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(2,5-dimethoxyphenyl)-8-methyl-; 1160254-47-6
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.