Description

2-(2,5-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a specialized quinoline derivative and a key acyl chloride intermediate used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its primary value lies in enabling the efficient introduction of the 2-(2,5-dimethylphenyl)-8-methylquinoline-4-carbonyl moiety, making it essential for chemists in fine chemical, pharmaceutical R&D, and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with quinoline-based structures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides where the quinoline scaffold imparts specific biological activity.
• Material Science Research: Acts as a precursor for creating advanced organic materials, including ligands for catalysts and components for organic electronic devices.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical research.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-(2,5-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160254-19-2
Molecular Formula	C20H16ClNO
Molecular Weight	321.80 g/mol
Synonyms	8-Methyl-2-(2,5-dimethylphenyl)quinoline-4-carbonyl chloride; 2-(2,5-Dimethylphenyl)-8-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(2,5-dimethylphenyl)-8-methyl-; 1160254-19-2; 2-(2,5-Dimethylphenyl)-8-methylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 2-(2,5-Dimethylphenyl)-8-Methylquinoline-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.