Description

2-(4-Isopropylphenyl)-6-Methylquinoline-4-Carbonyl Chloride is a specialized quinoline derivative and a key acyl chloride intermediate used in advanced organic synthesis. Its value lies in its high reactivity, which enables efficient construction of complex amide and ester bonds in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides requiring quinoline-based structures.
• Material Science Research: Serves as a precursor for creating functional organic materials, such as ligands for catalysts or components for organic electronics.
• Peptide Mimetic Chemistry: Facilitates the introduction of the quinoline-carbonyl moiety into peptide backbones to modify stability and bioactivity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-(4-Isopropylphenyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160253-55-3
Molecular Formula	C21H20ClNO
Molecular Weight	337.84 g/mol
Synonyms	6-Methyl-2-[4-(1-methylethyl)phenyl]-4-quinolinecarbonyl chloride; 2-(4-Isopropylphenyl)-6-methyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(4-isopropylphenyl)-6-methyl-; 2-(p-Isopropylphenyl)-6-methylquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Isopropylphenyl)-6-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global B2B partners in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.